[HTML][HTML] Age Related Changes in Muscle Mass and Force Generation in the Triple Transgenic (3xTgAD) Mouse Model of Alzheimer's Disease
… To investigate whether pathological changes associated with … used the triple transgenic
mouse model of AD (3xTgAD mice) that … We measured changes in motor neurons and skeletal …
mouse model of AD (3xTgAD mice) that … We measured changes in motor neurons and skeletal …
Age and gender differences for the behavioral phenotypes of 3xTg Alzheimer's disease mice
… of the triple transgenic Alzheimer’s disease (3xTg-AD) mice in … The difference between naïve
and trained activities of the 3xTg and … Age-related changes in neuroactive steroid levels in …
and trained activities of the 3xTg and … Age-related changes in neuroactive steroid levels in …
[HTML][HTML] Changes in 24 h rhythmicity of spontaneous locomotor activity in the triple transgenic mouse for Alzheimer's disease (3xTg-AD) in a jet lag protocol …
IA González-Luna, C Juárez-Tapia… - Journal of Circadian …, 2021 - ncbi.nlm.nih.gov
… the nocturnal locomotor activity, increased body temperature, … ) and triple transgenic mice
for Alzheimer disease (3xTg-AD). … age-related changes in the circadian system like changes in …
for Alzheimer disease (3xTg-AD). … age-related changes in the circadian system like changes in …
[HTML][HTML] Spatial coding defects of hippocampal neural ensemble calcium activities in the triple-transgenic Alzheimer's disease mouse model
… activities imaged at single cell resolution in a triple-transgenic Alzheimer's disease mouse
model (3xTg-AD) … pathological features along with age-related behavioral defects. To measure …
model (3xTg-AD) … pathological features along with age-related behavioral defects. To measure …
[HTML][HTML] Repurposing beta-3 adrenergic receptor agonists for Alzheimer's disease: beneficial effects in a mouse model
M Tournissac, TM Vu, N Vrabic, C Hozer… - Alzheimer's Research & …, 2021 - Springer
… to the triple transgenic mouse model of AD (3xTg-AD) and … multifactorial disease, with
frequent age-related comorbidities, … of body temperature, we noted that 3xTg-AD mice displayed …
frequent age-related comorbidities, … of body temperature, we noted that 3xTg-AD mice displayed …
[HTML][HTML] Disruption of oligodendrocyte progenitor cells is an early sign of pathology in the triple transgenic mouse model of Alzheimer's disease
I Vanzulli, M Papanikolaou, IC De-La-Rocha… - Neurobiology of …, 2020 - Elsevier
… undergo complex age-related remodeling in the hippocampus of the 3xTg-AD mouse model.
We … a detailed examination of age-related changes in OPC in the hippocampus of 3xTg-AD …
We … a detailed examination of age-related changes in OPC in the hippocampus of 3xTg-AD …
[HTML][HTML] Compromised astrocyte swelling/volume regulation in the hippocampus of the triple transgenic mouse model of Alzheimer's disease
J Tureckova, M Kamenicka, D Kolenicova… - Frontiers in Aging …, 2022 - frontiersin.org
… Already in 3-month-old 3xTg-AD mice, we detected a … Here we compare the age-related
changes with changes … This may indicate a reduced transcriptional activity in one …
changes with changes … This may indicate a reduced transcriptional activity in one …
Investigation of anxiety-and depressive-like symptoms in 4-and 8-Month-Old Male Triple Transgenic Mouse Models of Alzheimer's Disease
D Várkonyi, B Török, E Sipos, CL Fazekas… - International Journal of …, 2022 - mdpi.com
… investigate whether the triple-transgenic mouse (3xTg-AD) is … , the locomotor activity of the
3xTg-AD mice and controls did … animals compared to control, supporting age-related decline. …
3xTg-AD mice and controls did … animals compared to control, supporting age-related decline. …
Metabolic determinants of Alzheimer's disease: A focus on thermoregulation
M Tournissac, M Leclerc, J Valentin-Escalera… - Ageing Research …, 2021 - Elsevier
… Alzheimer’s disease (AD) is a complex age-related neurodegenerative … and maintenance
of body temperature. In recent years, the modulation of BAT activity has been increasingly …
of body temperature. In recent years, the modulation of BAT activity has been increasingly …
[HTML][HTML] Epigenetic studies in the male APP/BIN1/COPS5 triple-transgenic mouse model of Alzheimer's Disease
O Martínez-Iglesias, V Naidoo, I Carrera… - International Journal of …, 2022 - mdpi.com
… activity, may provide beneficial effects against age-related … activity and SIRT mRNA levels
were lower in APP/BIN1/COPS5 3xTg-AD than in wild-type mice; the transgenic AD mouse …
were lower in APP/BIN1/COPS5 3xTg-AD than in wild-type mice; the transgenic AD mouse …